Complete globozoospermia associated with PLCζ deficiency treated with calcium ionophore and ICSI results in pregnancy
نویسندگان
چکیده
منابع مشابه
Complete globozoospermia associated with DPY19L2 mutation treated with calcium ionophore ionomycin and ICSI results in live birth
The successful outcome of intracytoplasmic sperm injection (ICSI) with round-headed spermatozoa (globozoospermia) and ionomycin assisted activation oocytes is reported. A 30-year-old man with 100% globozoospermia underwent ICSI treatment. Real-time Polymerase Chain Reaction (PCR) detection indicates that the patient was DPY19L2 homozygous deletion. Nine metaphase II oocytes were injected with r...
متن کاملEffects of assisted oocyte activation with calcium- ionophore and strontium chloride on in vitro ICSI outcomes
Objective(s): Failed fertilization after intra-cytoplasmic sperm injection (ICSI) is mainly attributed to failed oocyte activation and can be overcome by artificial oocyte activation (AOA). The present study aims to compare in vitro outcomes of ICSI following two different assisted oocyte activation chemical procedures (SrCl2 and Ionomycin) in sibling oocytes of ICSI candidates.Materials and Me...
متن کاملPregnancy after the Calcium Ionophore Activation and Aneuploid Screening Using A-CGH in Globozoospermia Patient
Objective: To report a successful pregnancy after transfer of embryos derived from oocytes activated by calcium ionophore after intracytoplasmic sperm injection (ICSI) with round-headed sperms and aneuploid screening using aCGH. Design: Case report Setting: Private IVF clinic. Patient: A 28-year-old patients and her 31-year-old husband, diagnosed with 100% globozoospermia, underwent ICSI, oocyt...
متن کاملthe past hospitalization and its association with suicide attempts and ideation in patients with mdd and comparison with bmd (depressed type) group
چکیده ندارد.
A Successful Healthy Childbirth in a Case of Total Globozoospermia with Oocyte Activation by Calcium Ionophore
BACKGROUND Globozoospermia is a rare (incidence of 0.1% among andrological patients) and poorly understood condition, but a severe disorder in male infertility. This case report detailed the course of treatment and protocol of a patient with type 1 globozoospermia using Intracytoplasmic Sperm Injection (ICSI) and oocyte activation by calcium ionophore, which yielded conception and birth of a he...
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ژورنال
عنوان ژورنال: Reproductive BioMedicine Online
سال: 2010
ISSN: 1472-6483
DOI: 10.1016/j.rbmo.2009.12.024